LtaS-IN-1 |
| カタログ番号GC39633 |
LtaS-IN-1 (化合物 1771) は、多剤耐性 (MDR) 大腸菌におけるリポテイコ酸 (LTA) 合成の強力な低分子阻害剤です。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 877950-01-1
Sample solution is provided at 25 µL, 10mM.
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LtaS-IN-1 (compound 1771) is a potent small-molecule inhibitor of Lipoteichoic acid (LTA) synthesis in multidrug-resistant (MDR) E. faecium and by altering the cell wall morphology. LtaS-IN-1 alone inhibits Enterococcus.spp 28 strains with varying MIC values ranging from 0.5 μg/mL to 64 μg/mL. LtaS-IN-1 combination with antibiotics abolishs multidrug-resistant E. faecium growth almost completely[1].
[1]. Paganelli FL, et al. Lipoteichoic acid synthesis inhibition in combination with antibiotics abrogates growth of multidrug-resistant Enterococcus faecium.Int J Antimicrob Agents. 2017 Mar;49(3):355-363.
Average Rating: 5 (Based on Reviews and 3 reference(s) in Google Scholar.)
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