GLPBio

MrgprX2 antagonist-9

Catalog No.: GC79248Purity:>99.50%
COASDSData Sheet
MrgprX2 antagonist-9 is an MRGPRX2 antagonist with an IC50 of 0.1-100 nM.

製品は研究用途にのみ使用できます。人体には使用できません。患者への販売は行っておりません。

MrgprX2 antagonist-9
Cas No.: 3095296-92-4
10mM (in 1mL DMSO)In Stock
$756.00
1
1mgIn Stock
$236.00
1
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引用文献 (Citations)

現在、この製品の引用文献はありません。以下はGlpBio製品を引用した代表的な文献です。
  • Nature cover
    Nature
    641, 529–536 (2025)
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    Nature
    628, 630–638 (2024)
  • Nature cover
    Nature
    632, 686–694 (2024)
  • Nature cover
    Nature
    618, 1017–1023 (2023)
  • Nature cover
    Nature
    610, 366–372 (2022)
  • Cell cover
    Cell
    187(9):2288-2304 (2024)
  • Cell cover
    Cell
    183(7):1867-1883 (2020)
  • Science cover
    Science
    388(6745) (2025)
  • Science cover
    Science
    387(6739) (2025)
  • Science cover
    Science
    387(6734) (2025)
  • Cell Research cover
    Cell Research
    35, 97–116 (2025)
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    Cell Research
    34, 683–706 (2024)
  • Cell Research cover
    Cell Research
    33, 273–287 (2023)
  • Cell Research cover
    Cell Research
    33, 546–561 (2023)
  • Cell Research cover
    Cell Research
    33, 904–922 (2023)
  • Cell Research cover
    Cell Research
    31, 1291–1307 (2021)

製品説明 (Description)

MrgprX2 antagonist-9 is an MRGPRX2 antagonist with an IC50 of 0.1-100 nM. MrgprX2 antagonist-9 can be used for the research of inflammatory diseases [1].

In Vitro, MrgprX2 antagonist-9 (Compound 10) inhibits human MRGPRX2 activity with an IC50 of 0.1-100 nM in a β-Arrestin assay[1].

References:
[1]. Sabnis RW, et al. Novel Bicyclic Heterocycles as MRGPRX2 Antagonists for Treating Inflammatory Diseases. ACS Med Chem Lett. 2025;16(5):732-733. Published 2025 Apr 2.

製品資料 (Product Documents)

Purity:>99.50%Appearance:A solid
COASDSData Sheet

化学的性質 (Chemical Properties)

CAS番号
3095296-92-4
分子式
C21H20F6N6O
分子量
486.41
溶解性
DMSO: 100 mg/mL (205.59 mM; Need ultrasonic)
保存条件
Store at -20°C
配送条件
評価用サンプルは保冷剤とともに発送します。その他の容量は室温で発送し、ご要望に応じて保冷剤を同梱します。

計算ツール (Calculators)モル濃度 / 希釈 / 分子量 / 単位変換 / in vivo製剤 / 溶解度

g/mol

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