N-Formyl-MMYALF is a potent mitochondrial N-formyl peptide (mtFP) that has the activity of depleting calcium ions in the endoplasmic reticulum. N-Formyl-MMYALF can inhibit the FPR-1 -mediated chemotactic response of polymorphonuclear leukocytes (PMNs) to bacterial peptides [1].
References:
[1]. Kwon WY, et al. Circulating mitochondrial N-formyl peptides contribute to secondary nosocomial infection in patients with septic shock. Proc Natl Acad Sci U S A. 2021 Apr 27;118(17):e2018538118.
References:
[1]. Kwon WY, et al. Circulating mitochondrial N-formyl peptides contribute to secondary nosocomial infection in patients with septic shock. Proc Natl Acad Sci U S A. 2021 Apr 27;118(17):e2018538118.