GLPBio

ONO-AE 248

Catalog No.: GC83763Purity:>98.00%
COASDSData Sheet
ONO-AE 248 is a selective EP3 receptor agonist with cardioprotective activity.

製品は研究用途にのみ使用できます。人体には使用できません。患者への販売は行っておりません。

ONO-AE 248
Cas No.: 211230-67-0
10mM (in 1mL DMSO)In Stock
$292.00
1
5mgIn Stock
$266.00
1
10mgIn Stock
$425.00
1
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引用文献 (Citations)

現在、この製品の引用文献はありません。以下はGlpBio製品を引用した代表的な文献です。
  • Nature cover
    Nature
    641, 529–536 (2025)
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    Nature
    628, 630–638 (2024)
  • Nature cover
    Nature
    632, 686–694 (2024)
  • Nature cover
    Nature
    618, 1017–1023 (2023)
  • Nature cover
    Nature
    610, 366–372 (2022)
  • Cell cover
    Cell
    187(9):2288-2304 (2024)
  • Cell cover
    Cell
    183(7):1867-1883 (2020)
  • Science cover
    Science
    388(6745) (2025)
  • Science cover
    Science
    387(6739) (2025)
  • Science cover
    Science
    387(6734) (2025)
  • Cell Research cover
    Cell Research
    35, 97–116 (2025)
  • Cell Research cover
    Cell Research
    34, 683–706 (2024)
  • Cell Research cover
    Cell Research
    33, 273–287 (2023)
  • Cell Research cover
    Cell Research
    33, 546–561 (2023)
  • Cell Research cover
    Cell Research
    33, 904–922 (2023)
  • Cell Research cover
    Cell Research
    31, 1291–1307 (2021)

製品説明 (Description)

ONO-AE 248 is a selective EP3 receptor agonist with cardioprotective activity. ONO-AE 248 reduces myocardial infarction size by selectively binding to the EP3α receptor in mice. The cardioprotective effect of ONO-AE 248 is independent of hemodynamic effects. The mechanism of ONO-AE 248 may involve activation of protein kinase C and opening of K(ATP) channels [1].

References:
[1]. Selective activation of the prostanoid EP(3) receptor reduces myocardial infarct size in rodents

製品資料 (Product Documents)

Purity:>98.00%Appearance:An oil
COASDSData Sheet

化学的性質 (Chemical Properties)

CAS番号
211230-67-0
分子式
C22H36O5
分子量
380.52
溶解性
DMSO: ≥ 100 mg/mL (262.80 mM)
保存条件
Store at 4°C, protect from light, stored under nitrogen
配送条件
評価用サンプルは保冷剤とともに発送します。その他の容量は室温で発送し、ご要望に応じて保冷剤を同梱します。

計算ツール (Calculators)モル濃度 / 希釈 / 分子量 / 単位変換 / in vivo製剤 / 溶解度

g/mol

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