PF-00835231 |
| カタログ番号GC62133 |
PF-00835231 は CoV-2 システイン 3C 様プロテアーゼ (3CLpro) 阻害剤であり、SARS CoV-2 および SARS CoV-1 3CLpro の IC50 はそれぞれ 0.27 nM および 4 nM です。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 870153-29-0
Sample solution is provided at 25 µL, 10mM.
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PF-00835231 is a CoV-2 cysteine 3C-like protease (3CLpro) inhibitor, with IC50s of 0.27 nM and 4 nM for SARS CoV-2 and SARS CoV-1 3CLpro, respectively. PF-00835231 is developed for the research of anti-SARS-CoV-2/COVID-19[1].
[1]. Robert L Hoffman, et al. Discovery of Ketone-Based Covalent Inhibitors of Coronavirus 3CL Proteases for the Potential Therapeutic Treatment of COVID-19. J Med Chem. 2020 Nov 12;63(21):12725-12747.
Average Rating: 5 (Based on Reviews and 34 reference(s) in Google Scholar.)
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