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DDR1/DDR2 Receptor

DDR1/DDR2 receptors are unique receptor tyrosine kinases that bind to collagen and activated in several signaling pathways, including Shp-2, Src and MAPK. They have been associated with diseases like fibrosis, atherosclerosis and cancer.

Products Related to DDR1/DDR2 Receptor(1)

  • GC17365 structure
    GC17365DDR1-IN-1
    CAS: 1449685-96-4
    Purity: >98.00%

    DDR1-IN-1 は、強力かつ選択的な DDR1 受容体チロシンキナーゼ阻害剤であり、IC50 は 105 nM です。 DDR2 の 4 倍の効力 (IC50 = 413 nM)。