(S,S,S)-Icafolin-methyl

(S,S,S)-Icafolin-methyl is an isomer of Icafolin-methyl. Icafolin-methyl is a herbicide and plant β-tubulin ( Microtubule/Tubulin ) inhibitor. Icafolin-methyl binds to the β-tubulin region of the Colchicine binding site, thereby blocking the polymerization of plant tubulin. As a non-selective herbicide, Icafolin-methyl exhibits post-emergence activity against weeds in both cool-season and warm-season cropping systems, including resistant ryegrass and darnel biotypes. Icafolin-methyl can be used for herbicide research ^[1].

References:
[1]. Haaf KB, et al. The novel herbicide icafolin-methyl is a plant-specific inhibitor of tubulin polymerization. Pest Manag Sci. 2025;81(5):2652-2661.