GLPBio

SIRT1-IN-4

Catalog No.: GC84082Purity:>98.50%
COASDSData Sheet
SIRT1-IN-4 (Compound 8c) is a SIRT1 inhibitor, with an IC50 of 10.04 μM.

製品は研究用途にのみ使用できます。人体には使用できません。患者への販売は行っておりません。

SIRT1-IN-4
Cas No.: 445405-18-5
10mM (in 1mL DMSO)In Stock
$324.00
1
1mgIn Stock
$122.00
1
5mgIn Stock
$294.00
1
10mgIn Stock
$500.00
1
Tel: (909) 407-4943 / (909) 689-7124Email: sales@glpbio.com

引用文献 (Citations)

現在、この製品の引用文献はありません。以下はGlpBio製品を引用した代表的な文献です。
  • Nature cover
    Nature
    641, 529–536 (2025)
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    Nature
    628, 630–638 (2024)
  • Nature cover
    Nature
    632, 686–694 (2024)
  • Nature cover
    Nature
    618, 1017–1023 (2023)
  • Nature cover
    Nature
    610, 366–372 (2022)
  • Cell cover
    Cell
    187(9):2288-2304 (2024)
  • Cell cover
    Cell
    183(7):1867-1883 (2020)
  • Science cover
    Science
    388(6745) (2025)
  • Science cover
    Science
    387(6739) (2025)
  • Science cover
    Science
    387(6734) (2025)
  • Cell Research cover
    Cell Research
    35, 97–116 (2025)
  • Cell Research cover
    Cell Research
    34, 683–706 (2024)
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    Cell Research
    33, 273–287 (2023)
  • Cell Research cover
    Cell Research
    33, 546–561 (2023)
  • Cell Research cover
    Cell Research
    33, 904–922 (2023)
  • Cell Research cover
    Cell Research
    31, 1291–1307 (2021)

製品説明 (Description)

SIRT1-IN-4 (Compound 8c) is a SIRT1 inhibitor, with an IC50 of 10.04 μM. SIRT1-IN-4 can be used for the research of cancer [1].

References:
[1]. Li C, et al. Discovery of 5-Benzylidene-2-phenyl-1,3-dioxane-4,6-diones as Highly Potent and Selective SIRT1 Inhibitors. ACS Med Chem Lett. 2021 Mar 1;12(3):397-403.

製品資料 (Product Documents)

Purity:>98.50%Appearance:A solid
COASDSData Sheet

化学的性質 (Chemical Properties)

CAS番号
445405-18-5
分子式
C25H18O7
分子量
430.41
溶解性
DMSO: 100 mg/mL (232.34 mM; Need ultrasonic)
保存条件
Store at 4°C, protect from light
配送条件
評価用サンプルは保冷剤とともに発送します。その他の容量は室温で発送し、ご要望に応じて保冷剤を同梱します。

計算ツール (Calculators)モル濃度 / 希釈 / 分子量 / 単位変換 / in vivo製剤 / 溶解度

g/mol

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