SPHINX31 |
| カタログ番号GC19456 |
SPHINX31 は強力で選択的な SRPK1 阻害剤で、IC50 は 5.9 nM です。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1818389-84-2
Sample solution is provided at 25 µL, 10mM.
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SPHINX31 is a potent and selective inhibitor of serine/arginine-rich protein kinase 1 (SRPK1), with an IC50 of 5.9 nM. SPHINX31 inhibits phosphorylation of serine/arginine-rich splicing factor 1 (SRSF1). SPHINX31 is a potential topical therapeutic for neovascular eye disease[1].
References:
[1]. Batson J, et al. Development of Potent, Selective SRPK1 Inhibitors as Potential Topical Therapeutics for Neovascular Eye Disease. ACS Chem Biol. 2017 Mar 17;12(3):825-832.
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