GLPBio

AV5116

Catalog No.: GC78868Purity:>99.50%
COASDSData Sheet
AV5116 is a cap-dependent endonuclease inhibitor ( CENI ) that binds to the active site of the cap-dependent endonuclease (CEN) located in the N-terminal domain of the polymerase acidic.

제품은 연구용으로만 사용됩니다. 인체에 사용할 수 없으며 환자에게 판매하지 않습니다.

AV5116
Cas No.: 2417851-90-0
10mM (in 1mL DMSO)In Stock
$77.00
1
5mgIn Stock
$71.00
1
10mgIn Stock
$115.00
1
25mgIn Stock
$230.00
1
50mgIn Stock
$367.00
1
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  • Nature cover
    Nature
    641, 529–536 (2025)
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    Nature
    628, 630–638 (2024)
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    Nature
    632, 686–694 (2024)
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    Nature
    618, 1017–1023 (2023)
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    Nature
    610, 366–372 (2022)
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    Cell
    187(9):2288-2304 (2024)
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    Cell
    183(7):1867-1883 (2020)
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    Science
    388(6745) (2025)
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    387(6739) (2025)
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    Science
    387(6734) (2025)
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    Cell Research
    35, 97–116 (2025)
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    34, 683–706 (2024)
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    33, 273–287 (2023)
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    33, 546–561 (2023)
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    33, 904–922 (2023)
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    31, 1291–1307 (2021)

제품 설명 (Description)

AV5116 is a cap-dependent endonuclease inhibitor ( CENI ) that binds to the active site of the cap-dependent endonuclease (CEN) located in the N-terminal domain of the polymerase acidic. AV5116 exhibits potent inhibitory activity against influenza viruses (influenza A, B, and C viruses). AV5116 can be used for the study of influenza virus infections [1].

References:
[1]. Chesnokov A, et al. Influenza C virus susceptibility to antivirals with different mechanisms of action. Antimicrob Agents Chemother. 2024 May 2;68(5):e0172723.

제품 문서 (Product Documents)

Purity:>99.50%Appearance:A solid
COASDSData Sheet

화학적 특성 (Chemical Properties)

CAS 번호
2417851-90-0
분자식
C22H17F2N3O4S2
분자량
489.51
용해도
DMSO: 25 mg/mL (51.07 mM; Need ultrasonic)
보관
Store at -20°C
배송 조건
평가용 샘플은 아이스팩과 함께 배송됩니다. 그 외 용량은 실온 배송되며, 요청 시 아이스팩과 함께 배송할 수 있습니다.

계산 도구 (Calculators)몰 농도 / 희석 / 분자량 / 단위 변환 / 생체 내 제형 / 용해도

g/mol

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