Chalcone is isolated from Glycyrrhizae inflata and used to synthesize chalcone derivatives. Chalcone derivatives possess varied biological and pharmacological activity, including anti-inflammatory, antioxidative, antibacterial, anticancer, and anti-parasitic activities[1].
Chalcone derivatives are synthesized by Claisen-Shimidt base-catalyzed condensation of appropriate aromatic ketones or substituted aromatic ketones with benzaldehydes or substituted benzaldehydes[1].
[1]. Shailendra Mandge,et al. Synthesis and Characterization of Some Chalcone Derivatives. Trends in Applied Sciences Research Volume 2 (1): 52-56, 2007