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CRTH2

CRTh2 (chemoattractant receptor homologous molecule expressed on T-Helper type 2 cells ) is a G-protein coupled receptor for prostaglandin D2. Activation of CRTh2 increases the chemotaxis of Th2 cells/eosinophils/basophil, as well as eosinophil degranulation and Th2 cells cytokine release.

Products Related to CRTH2(2)

  • GC12434 structure
    GC12434AZD1981
    CAS: 802904-66-1
    Purity: >99.50%

    AZD1981은 강력하고 선택적인 CRTh2 길항제입니다. 높은 효능으로 인간 재조합 DP2에서 방사성 표지된 PGD2를 대체합니다(pIC50 = 8.4).

  • GC13196 structure
    GC13196NVP-QAV680
    CAS: 872365-16-7
    Purity: >98.00%

    potent and selective CRTh2 receptor antagonist