Endocannabinoid/Endocannabinoid-like

Noladin ether는 21.2 nM의 Ki를 갖는 칸나비노이드 CB1 수용체의 강력하고 선택적인 작용제입니다.

N-Arachidonoyl Dopamine은 Ki가 250nM인 강력하고 선택적인 내인성 CB1 수용체 작용제입니다.

An endocannabinoid

Prostaglandin E1 ethanolamide (PGE1-EA) is the ethanolamine-amide analog of PGE1.

A stable analog of PGF 2α 2glyceryl ester

Polyunsaturated fatty acids such as arachidonate and linoeate, while essential to health maintenance, are subject to random peroxidation by ambient oxygen, resulting in fragmented and reactive decomposition products.

Synaptamide (Dehydroepiandrosteron(DHEA))는 cAMP 생성을 자극하는 내인성 GPR110(ADGRF1) 리간드로 EC₅₀ 값이 1.27 nM이다 .

R-2 methanandamide is a cannabinoid analog with a methyl group in the (R) configuration at C-2 of the ethanolamine group.

2-Arachidonoyl glycerol (2-AG) has been isolated from porcine brain, and has been characterized as the natural endocannabinoid ligand for the CB1 receptor.

2-O-Hexadecyl Glycerol is a β-monoglyceride of palmitic acid.

N-Acylated ethanolamines (NAE) are naturally-occurring lipids that have diverse bioactivities.

The glyceryl esters of arachidonic acid have been proposed as endogenous cannabinoid ligands.

Docosaenoyl ethanolamide is a member of the family of fatty N-acyl ethanolamines collectively called endocannabinoids.

The endocannabinoids present a rich system of central cannabinoid (CB1), peripheral cannabinoid (CB2), and non-CB receptor-mediated pharmacology that has stimulated research in many fields including memory, weight loss and appetite, neurodegeneration, tumor surveillance, analgesia, and inflammation.

γ-Linolenoyl ethanolamide is a member of the family of fatty N-acyl ethanolamines collectively called endocannabinoids.

Fatty acid amide hydrolase (FAAH) is the enzyme responsible for hydrolysis and inactivation of fatty acid amides including anandamide and oleamide.

The enzyme, fatty acid amide hydrolase (FAAH), is widely expressed in brain and other tissues, and is capable of hydrolyzing anandamide (AEA) and other simple esters and amides with long unsaturated acyl chains.

Fatty acid amide hydrolase (FAAH) is the enzyme responsible for hydrolysis and inactivation of fatty acid amides including anandamide and oleamide.

MAGL 억제제 화합물 23은 80nM의 IC50으로 MAGL의 강력하고 선택적이고 가역적이며 경쟁적인 억제제입니다. MAGL 억제제 화합물 23은 인간 유방암, 결장직장암 및 난소암 세포에 대해 항증식 효과를 나타냅니다. MAGL 억제제 화합물 23은 세포 기반 및 생체 내 분석에서 MAGL을 차단합니다.

N-acylethanolamines (NAEs) are lipid-derived signaling compounds.

(±)17(18)-EpETE-Ethanolamide is an ω-3 endocannabinoid epoxide.

N-(1-(3,4-Dihydroxyphenyl)propan-2-yl)oleamide binds to the cannabinoid 1 (CB1) receptor with a Ki value of 365 nM in a radioligand binding assay using rat brain homogenate.

Palmitoyl ethanolamide (PEA) is an endogenous cannabinoid found in brain, liver, and other mammalian tissues.

URB754는 IC50이 200nM인 체내칸나비노이드 비활성화 효소 모노아실글리세롤 리파제(MGL)의 강력한 억제제입니다.