Flunisolide is a fluorinated corticosteroid receptor agonist that induces reversible pyloric hyalinization in CD-1 mice following oral administration at a dose of 200 μg/kg per day.[1] Formulations containing flunisolide have been used for the treatment of asthma.[2]
Reference:
[1]. McKevitt, T.P., Giffen, P., Woodfine, J.A., et al. Hyalinization of the pyloric stomach in CD-1 mice following oral (dietary) administration of the corticosteroid agonists mometasone furoate, budesonide, and flunisolide. Toxicol. Pathol. 39(6), 958-968 (2011).
[2]. O'Callaghan, C., White, J.A., and Kantar, A. Nebulization of corticosteroids to asthmatic children: Large variation in dose inhaled. Respirology 19(2), 276-279 (2014).