Silvestrol aglycone |
| Catalog No.GC37638 |
실베스트롤 아글리콘은 myc-LUC 및 tub-LUC 루시페라제 리포터 단백질 번역에 대해 각각 10 및 200nM의 EC50으로 암 세포에서 단백질 번역 개시를 억제하는 실베스트롤 유사체입니다. 항암 활성.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 960365-65-5
Sample solution is provided at 25 µL, 10mM.
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Silvestrol aglycone is a Silvestrol analogue, inhibits protein translation initiation in cancer cells, with EC50s of 10 and 200 nM for myc-LUC and tub-LUC luciferase reporter protein translation, respectively. Anti-cancer activity[1].
Silvestrol aglycone (Compound 4) inhibits the proliferation of MDA-MB-231 cells with an E50 of 20 ± 10 nM after 72 h[1].
[1]. Liu T, et al. Synthetic silvestrol analogues as potent and selective protein synthesis inhibitors. J Med Chem. 2012 Oct 25;55(20):8859-78.
Average Rating: 5 (Based on Reviews and 5 reference(s) in Google Scholar.)
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