GLPBio

Menin-MLL

Menin-MLL interaction is a drug target for leukemia treatment. Menin is a multiple endocrine neoplasia (MEN1) products which interacts with MLL (mixed lineage leukemia) in a histone methyltransferase complex.

Products Related to Menin-MLL(5)

  • GC10388 structure
    GC10388MI-2 (hydrochloride)
    Purity: >98%

    menin-MLL interaction inhibitor

  • GC11418 structure
    GC11418MI-2
    CAS: 1271738-62-5
    Purity: >99.00%

    An inhibitor of menin-MLL fusion protein interactions

  • GC11837 structure
    GC11837MI-136
    CAS: 1628316-74-4
    Purity: >98.50%

    MI-136은 IC50이 31nM이고 Kd가 23.6nM인 메닌-MLL 단백질-단백질 상호작용(PPI)의 억제제입니다. MI-136은 AR 신호 전달을 차단하는 것으로 나타났으며 거세 저항성 종양에 대한 연구 가능성이 있습니다.

  • GC12173 structure
    GC12173MI-nc (hydrochloride)
    CAS: 1934302-23-4
    Purity: >98%

    weak inhibitor of menin-MLL interaction

  • GC12199 structure
    GC12199MI-3
    CAS: 1271738-59-0
    Purity: >98.00%

    An inhibitor of menin-MLL fusion protein interactions