NF-κβ activator 1 |
| Catalog No.GC62344 |
NF-κβ 활성제 1은 강력한 NF-6입니다. EC50이 0.9인 활성제 μM.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2387524-59-4
Sample solution is provided at 25 µL, 10mM.
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NF-κβ activator 1 is a potent NF-κβ activator with an EC50 of 0.9 μM. NF-κβ activator 1 induces superoxide dismutase (SOD)2 mRNA expression[1].
NF-κβ activator 1 (compound 32) (1 μM; 6 hours) induces SOD2 mRNA expression in SH-SY5Y neuroblastoma cells[1].
[1]. Mathew B, et al. Structure-activity relationship (SAR) studies of N-(3-methylpyridin-2-yl)-4-(pyridin-2-yl)thiazol-2-amine (SRI-22819) as NF-?B activators for the treatment of ALS [published online ahead of print, 2020 Oct 22]. Eur J Med Chem. 2020;112952.
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