Reactive Probes

MTSSL is a paramagnetic nitroxide spin label featuring a methanethiosulfonate group for site-directed spin labeling, particularly through disulfide linkages with cysteine residues on proteins.

Direct Red 80(Sirius Red)은 콜라겐 및 아밀로이드 염색 방법에 주로 사용되는 폴리아조 염료입니다.

YnMyr Diazirine X10 is a cell-permeable photoreactive probe for protein myristoylation.

12(S)-HETE is the predominant lipoxygenase product of mammalian platelets.

4-oxo-2-Nonenal is a product of lipid peroxidation that actively modifies histidine and lysine residues on proteins and causes protein cross-linking.

α-D-Galactopyranosylphenyl isothiocyanate is a chemically activated form of galactose that has been used to prepare various neoglycoproteins, which consist of a glycosylated serum albumin substituted with either fluorescein or methotrexate.

S-Nitrosylation reactions regulate protein function and mediate nitrosative stress.

Redox-sensitive cysteine residues in proteins may function as sensors of reactive oxygen species (ROS) and also serve as molecular switches, activating or deactivating proteins, following a change in oxidation state.

BCN-E-BCN is a strained cycloalkyne probe for detecting proteins that have been sulfenylated, the first intermediate step in protein oxidation.

A hydrophobic spin label

4'-Aminomethyl-4,5',8-trimethylpsoralen is a bifunctional photoreactive agent for crosslinking nucleic acids.

9,10-Anthracenediyl-bis(methylene)dimalonic Acid은 안트라센의 수용성 유도체이고 일반적으로 단일 산소 프로브로 사용된다. 9,10-Anthracenediyl-bis(methylene)dimalonic Acid은 단일 산소에 의해 그에 해당하는 내과 산화물로 광백색화될 수 있고 380-400nm에서의 흡광도를 시간 의존적으로 줄어들게 한다.

DNA는 내적 및 환경 요인에 의해 지속적으로 손상을 입어, 아베이식 (apurinic / apyrimidinic, AP) 부위가 형성되어 DNA 합성에 방해가 됩니다.

DAz-2 is a cell-permeable chemical probe used to detect cysteine oxidation in proteins.

cDEPMPO는 강력한 항암 전구약물입니다. 고농도의 DEPMPO는 1전자 환원된 BTO(benzotriazine 1,4-di-N-oxide) 화합물에서 발생하는 아릴 라디칼과 함께 .OH 라디칼을 스핀 트랩합니다.

Disuccinimidyl Sulfoxide (DSSO)는 균일 이기능성, 아민 대상, 술폭사이드를 포함한 크로스링커로 크로스링크 마스 스펙트로메트리(XL-MS)를 통해 단백질-단백질 상호작용(PPIs)을 분석하는 데 사용된다.

IBTP is a lipophilic cation that is accumulated in mitochondria and forms stable thioether adducts in a thiol-specific manner.

MTSEA-biotin is a thiol-reactive probe that can be used to label proteins at cysteine residues.

Methanethiosulfonates (MTS) are sulfhydryl-reactive compounds that form mixed disulfide linkages and are commonly used to study cysteine residues on proteins.

MTSET (chloride) is a methanethiosulfonate (MTS), a sulfhydryl-reactive compound that forms mixed disulfide linkages.

Labeling reactive centers of various types in cells with specific site-directed probes is a common method to explore both function and biochemical modification of proteins.

SNOB 1 Reagent is a biotinylated probe for detecting S-nitrosylated proteins in a single step.

An internal standard for the quantification of Girard’s reagent P

5-Ethynyluridine(5-EU)은 강력한 세포 투과성 뉴클레오사이드로 새로 합성된 RNA를 표지하는 데 사용할 수 있습니다.