TK05 |
| Catalog No.GC65438 |
TK05는 IC50이 95nM인 류코트리엔 C4 합성효소(LTC4S)의 강력하고 선택적인 억제제입니다.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1245734-61-5
Sample solution is provided at 25 µL, 10mM.
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TK05 is a potent and selective inhibitor of leukotriene C4 synthase (LTC4S) with an IC50 of 95 nM[1].
TK05 reduces LTC4 production in a dose-dependent manner with an IC50 value of 318 ± 60 nM in MM6 Cells[1].
TK05 (0.12-6 mg/kg; given i.p.; only once) significantly reduces LTE4 levels[1].
[1]. Kleinschmidt TK, et al. Tandem Benzophenone Amino Pyridines, Potent and Selective Inhibitors of Human Leukotriene C4 Synthase. J Pharmacol Exp Ther. 2015 Oct;355(1):108-16.
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