ZER1 binder-2 is a ZER1 E3 ubiquitin ligase binder with an EC 50 value of 51.04 nM. ZER1 binder-2 is applicable to the research of cancers induced by HPV infection [1].
In Vitro, ZER1 binder-2 (Example 313) binds to the purified ZER1 (469-766) protein in fluorescence polarization assays, with an EC50 of 51.04 nM[1].
References:
[1]. HENDERSON, et al. ZER1 BINDERS, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF. WO2026122416. PCT. 11.06.2026.
In Vitro, ZER1 binder-2 (Example 313) binds to the purified ZER1 (469-766) protein in fluorescence polarization assays, with an EC50 of 51.04 nM[1].
References:
[1]. HENDERSON, et al. ZER1 BINDERS, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF. WO2026122416. PCT. 11.06.2026.