GLPBio

Lib2-1

Catalog No.: GC72306Purity:>99.00%
Lib2-1, a macrocyclic peptide, is an IL-17C/IL-17RE interaction inhibitor.

Products are for research use only. Not for human use. We do not sell to patients.


Lib2-1
Cas No.: 2983116-47-6
1 mgIn Stock
$68.00
1
5 mgIn Stock
$167.00
1
10 mgIn Stock
$270.00
1
25 mgIn Stock
$540.00
1

Citations

No citations are currently available for this product. Below are selected publications citing GlpBio products.
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    Nature
    641, 529–536 (2025)
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    628, 630–638 (2024)
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    632, 686–694 (2024)
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    618, 1017–1023 (2023)
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    Nature
    610, 366–372 (2022)
  • Cell cover
    Cell
    187(9):2288-2304 (2024)
  • Cell cover
    Cell
    183(7):1867-1883 (2020)
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    Science
    388(6745) (2025)
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    387(6739) (2025)
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    387(6734) (2025)
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    Cell Research
    35, 97–116 (2025)
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    34, 683–706 (2024)
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    33, 273–287 (2023)
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    33, 546–561 (2023)
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    33, 904–922 (2023)
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    31, 1291–1307 (2021)

Description

Lib2-1, a macrocyclic peptide, is an IL-17C/IL-17RE interaction inhibitor. Lib2-1 can be used for autoimmune and inflammatory diseases research.

References:
[1]. Silong Zhai, et al. PepScaf: Harnessing Machine Learning with In Vitro Selection toward De Novo Macrocyclic Peptides against IL-17C/IL-17RE Interaction. J Med Chem. 2023 Aug 24;66(16):11187-11200.

Product Documents

Purity:>99.00%Appearance:A solid

Chemical Properties

CAS No.
2983116-47-6
Molecular Formula
C81H108N18O23S
Molecular Weight
1733.9
Solubility
DMSO : 100 mg/mL (57.67 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Storage
Sealed storage, away from moisture
General tips
Select a suitable solvent according to the product solubility data. Once prepared, aliquot the stock solution to avoid repeated freeze-thaw cycles.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.

CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility

g/mol

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