GLPBio

LIBX-A401

Catalog No.: GC91949Purity:>95.00%
COASDSData Sheet
LIBX-A401 is an inhibitor of long-chain acyl-CoA synthetase 4 (ACSL4; IC50 = 0.38 ?M).

Products are for research use only. Not for human use. We do not sell to patients.

LIBX-A401
5 mgIn Stock
$45.00
1
10 mgIn Stock
$85.00
1
50 mgIn Stock
$358.00
1
100 mgIn Stock
$672.00
1
Tel: (909) 407-4943 / (909) 689-7124Email: sales@glpbio.com

Citations

No citations are currently available for this product. Below are selected publications citing GlpBio products.
  • Nature cover
    Nature
    641, 529–536 (2025)
  • Nature cover
    Nature
    628, 630–638 (2024)
  • Nature cover
    Nature
    632, 686–694 (2024)
  • Nature cover
    Nature
    618, 1017–1023 (2023)
  • Nature cover
    Nature
    610, 366–372 (2022)
  • Cell cover
    Cell
    187(9):2288-2304 (2024)
  • Cell cover
    Cell
    183(7):1867-1883 (2020)
  • Science cover
    Science
    388(6745) (2025)
  • Science cover
    Science
    387(6739) (2025)
  • Science cover
    Science
    387(6734) (2025)
  • Cell Research cover
    Cell Research
    35, 97–116 (2025)
  • Cell Research cover
    Cell Research
    34, 683–706 (2024)
  • Cell Research cover
    Cell Research
    33, 273–287 (2023)
  • Cell Research cover
    Cell Research
    33, 546–561 (2023)
  • Cell Research cover
    Cell Research
    33, 904–922 (2023)
  • Cell Research cover
    Cell Research
    31, 1291–1307 (2021)

Description

LIBX-A401 is an inhibitor of long-chain acyl-CoA synthetase 4 (ACSL4; IC50 = 0.38 ?M).1 It is selective for ACSL4 over ACSL3 (IC50 = >50 ?M) and peroxisome proliferator-activated receptor γ (PPARγ; IC50 = >10 ?M).

References:
[1]. Dorooee, D.M., Ravez, S., Vertommen, D., et al.LIBX-A401: A novel selective inhibitor of acyl-coa synthetase long chain family member 4 (ACSL4) and its binding modeChemRxiv(2024).

Product Documents

Purity:>95.00%Appearance:A solid
COASDSData Sheet

Chemical Properties

Chemical Name
methyl (E)-3-(4-(2-(N-methylbenzamido)ethoxy)phenyl)acrylate
SMILES
CN(C(C1=CC=CC=C1)=O)CCOC2=CC=C(/C=C/C(OC)=O)C=C2
Molecular Formula
C20H21NO4
Molecular Weight
339.4
Solubility
Ethanol: Slightly soluble: 0.1-1 mg/ml
Storage
-20°C
General tips
Select a suitable solvent according to the product solubility data. Once prepared, aliquot the stock solution to avoid repeated freeze-thaw cycles.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.

CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility

g/mol

Reviews

Review for LIBX-A401

Rating: 5
  • 5 Star100%
  • 4 Star0%
  • 3 Star0%
  • 2 Star0%
  • 1 Star0%