GLPBio

LUF8100

Catalog No.: GC27835Purity:>98.50%
COASDSData Sheet

LUF8100 is a dual-target antagonist of CCR2/CCR5 with pKi values for CCR2 and CCR5 of 5.23 and 4.97 respectively.

Products are for research use only. Not for human use. We do not sell to patients.

LUF8100
Cas No.: 2954281-30-0
10mM (in 1mL DMSO)In Stock
$98.00
1
5mgIn Stock
$89.00
1
10mgIn Stock
$130.00
1
25mgIn Stock
$235.00
1
50mgIn Stock
$373.00
1
Tel: (909) 407-4943 / (909) 689-7124Email: sales@glpbio.com

Citations

No citations are currently available for this product. Below are selected publications citing GlpBio products.
  • Nature cover
    Nature
    641, 529–536 (2025)
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    Nature
    628, 630–638 (2024)
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    Nature
    632, 686–694 (2024)
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    618, 1017–1023 (2023)
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    Nature
    610, 366–372 (2022)
  • Cell cover
    Cell
    187(9):2288-2304 (2024)
  • Cell cover
    Cell
    183(7):1867-1883 (2020)
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    Science
    388(6745) (2025)
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    387(6739) (2025)
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    387(6734) (2025)
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    Cell Research
    35, 97–116 (2025)
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    34, 683–706 (2024)
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    33, 273–287 (2023)
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    33, 546–561 (2023)
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    33, 904–922 (2023)
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    Cell Research
    31, 1291–1307 (2021)

Description

LUF8100 is a dual-target antagonist of CCR2/CCR5 with pKi values for CCR2 and CCR5 of 5.23 and 4.97 respectively. LUF8100 can be used for research on immune homeostasis and cancer[1].

References:
[1]. Essa K, et al. Combining AlphaFold with Focused Virtual Library Design in the Development of Novel CCR2 and CCR5 Antagonists. J Chem Inf Model. 2025 Nov 24;65(22):12398-12409.

Product Documents

Purity:>98.50%Appearance:A solid
COASDSData Sheet

Chemical Properties

CAS No.
2954281-30-0
Chemical Name
Benzenesulfonamide, 4-chloro-N-[3-(2-oxo-1-piperidinyl)phenyl]-3-(trifluoromethyl)-
SMILES
O=S(NC1=CC(N2CCCCC2)=CC=C1)(C3=CC=C(Cl)C(C(F)(F)F)=C3)=O
Molecular Formula
C18H18ClF3N2O2S
Molecular Weight
418.86
Solubility
DMSO : ≥ 100 mg/mL (238.74 mM)
Storage
-20°C
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.

CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility

g/mol

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