GLPBio

m-APTA

Catalog No.: GC83458Purity:>99.50%Synonyms: 5′-S-(3-Aminophenyl)-5′-thioadenosine
COASDSData Sheet
m-APTA (5'-S-(3-aminophenyl)-5'-thioadenosine) is a selective chemoprotective agent targeting methylthioadenosine phosphorylase ( MTAP ).

Products are for research use only. Not for human use. We do not sell to patients.

m-APTA
Cas No.: 86072-47-1
10mM (in 1mL DMSO)In Stock
$73.00
1
5mgIn Stock
$67.00
1
10mgIn Stock
$100.00
1
25mgIn Stock
$200.00
1
50mgIn Stock
$300.00
1
100mgIn Stock
$450.00
1
Tel: (909) 407-4943 / (909) 689-7124Email: sales@glpbio.com

Citations

No citations are currently available for this product. Below are selected publications citing GlpBio products.
  • Nature cover
    Nature
    641, 529–536 (2025)
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    Nature
    628, 630–638 (2024)
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    Nature
    632, 686–694 (2024)
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    618, 1017–1023 (2023)
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    Nature
    610, 366–372 (2022)
  • Cell cover
    Cell
    187(9):2288-2304 (2024)
  • Cell cover
    Cell
    183(7):1867-1883 (2020)
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    Science
    388(6745) (2025)
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    387(6739) (2025)
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    387(6734) (2025)
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    Cell Research
    35, 97–116 (2025)
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    34, 683–706 (2024)
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    33, 273–287 (2023)
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    33, 546–561 (2023)
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    33, 904–922 (2023)
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    Cell Research
    31, 1291–1307 (2021)

Description

m-APTA (5'-S-(3-aminophenyl)-5'-thioadenosine) is a selective chemoprotective agent targeting methylthioadenosine phosphorylase ( MTAP ). m-APTA can be converted into adenine, which is a crucial step in protecting normal cells from the toxicity of nucleobase analogues (NBA). m-APTA is promising for research of MTAP-deficient cancers [1].

References:
[1]. Zhang S, et al. 5'-S-(3-aminophenyl)-5'-thioadenosine, a novel chemoprotective agent for reducing toxic side effects of fluorouracil in treatment of MTAP-deficient cancers. Mol Cancer Ther. 2025 Mar 10.

Product Documents

Purity:>99.50%Appearance:A solid
COASDSData Sheet

Chemical Properties

CAS No.
86072-47-1
Synonyms
5′-S-(3-Aminophenyl)-5′-thioadenosine
Molecular Formula
C16H18N6O3S
Molecular Weight
374.42
Solubility
DMSO: 100 mg/mL (267.08 mM; Need ultrasonic)
Storage
Store at -20°C
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.

CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility

g/mol

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