MoTP, known more formally as 4-(4-morpholinobutylthio)phenol, is used to ablate larval melanocytes in zebrafish in order to study melanocyte regeneration. MoTP is converted to a cytotoxin in cells with high tyrosinase activity, which in the zebrafish embryo are limited to melanoblasts and newly formed melanocytes. The wash-out of MoTP allows regeneration through the proliferation of melanocyte stem cells.
MoTP
Catalog No.: GC44245Purity:>98.00%Synonyms: 4(4Morpholinylbutylthio)phenol
MoTP, known more formally as 4-(4-morpholinobutylthio)phenol, is used to ablate larval melanocytes in zebrafish in order to study melanocyte regeneration.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 57055-82-0
1mgIn Stock
$49.00
1
5mgIn Stock
$132.00
1
10mgIn Stock
$214.00
1
25mgIn Stock
$413.00
1
| Pack Size | Price | Availability | Quantity | Action |
|---|---|---|---|---|
| 1mg | $49.00 | In Stock | 1 | |
| 5mg | $132.00 | In Stock | 1 | |
| 10mg | $214.00 | In Stock | 1 | |
| 25mg | $413.00 | In Stock | 1 |
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Citations
No citations are currently available for this product. Below are selected publications citing GlpBio products.
Nature641, 529–536 (2025)
Nature628, 630–638 (2024)
Nature632, 686–694 (2024)
Nature618, 1017–1023 (2023)
Nature610, 366–372 (2022)
Cell187(9):2288-2304 (2024)
Cell183(7):1867-1883 (2020)
Science388(6745) (2025)
Science387(6739) (2025)
Science387(6734) (2025)
Cell Research35, 97–116 (2025)
Cell Research34, 683–706 (2024)
Cell Research33, 273–287 (2023)
Cell Research33, 546–561 (2023)
Cell Research33, 904–922 (2023)
Cell Research31, 1291–1307 (2021)
Description
Product Documents
Purity:>98.00%Appearance:A solid
Chemical Properties
CAS No.
57055-82-0
Synonyms
4(4Morpholinylbutylthio)phenol
SMILES
OC1=CC=C(SCCCCN2CCOCC2)C=C1
Molecular Formula
C14H21NO2S
Molecular Weight
267.4
Solubility
DMF: 33 mg/ml,DMSO: 25 mg/ml,Ethanol: 0.3 mg/ml,PBS (pH 7.2): 5 mg/ml
Storage
Store at -20°C
General tips
Select a suitable solvent according to the product solubility data. Once prepared, aliquot the stock solution to avoid repeated freeze-thaw cycles.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.
CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility
g/mol
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