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mPEG2000-DPG

Catalog No.GC79691 Copy One-Click Copy Product Info

mPEG2000-DPG is a PEG-based lipid that can be used to formulate lipid nanoparticles for drug delivery.

Products are for research use only. Not for human use. We do not sell to patients.

mPEG2000-DPG Chemical Structure

Cas No.: 162409-28-1

Size Price Stock Qty
5mg
$24.00
In stock
10mg
$38.00
In stock
25mg
$76.00
In stock
50mg
$121.00
In stock
100mg
$194.00
In stock

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Customer Reviews

Based on customer reviews.

Sample solution is provided at 25 µL, 10mM.



Description of mPEG2000-DPG

mPEG2000-DPG is a PEG-based lipid that can be used to formulate lipid nanoparticles for drug delivery.

In Vitro, Lipids used to prepare nanoparticles are a class of amphiphilic biomolecules that combine structural diversity, biocompatibility, and functional tunability. As the core framework of nanodelivery systems, they not only form lipid bilayers or solid matrices through self-assembly to encapsulate lipophilic or hydrophilic drugs, but can also be further subdivided according to formulation requirements into structural lipids (such as phospholipids and triglycerides), functional lipids (such as ionizable cationic lipids used for nucleic acid condensation and endosome escape), and sterically stable lipids (such as PEGylated lipids).

Chemical Properties of mPEG2000-DPG

Cas No. 162409-28-1 SDF
Formula (C2H4O)nC36H70O5 M.Wt 2000
Solubility DMSO: 100 mg/mL (Need ultrasonic) Storage Store at -20°C
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of mPEG2000-DPG

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 500 μL 2.5 mL 5 mL
5 mM 100 μL 500 μL 1 mL
10 mM 50 μL 250 μL 500 μL
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**When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and MSDS / CoA (available online).

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In vivo Formulation Calculator (Clear solution) of mPEG2000-DPG

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

mg/kg g μL

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO % % Tween 80 % saline
%DMSO %

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL saline, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

Product Documents

Quality Control & SDS

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Average Rating: 5 ★★★★★ (Based on Reviews and 30 reference(s) in Google Scholar.)

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