GLPBio

N-Palmitoyl Phenylalanine

Catalog No.: GC91996Purity:>95.00%Synonyms: N-Hexadecanoyl Phenylalanine
COASDSData Sheet
N-Palmitoyl phenylalanine is an N-acyl amide that contains the long-chain saturated fatty acid palmitic acid conjugated via an amide bond to the essential amino acid L-phenylalanine.

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N-Palmitoyl Phenylalanine
Cas No.: 37571-96-3
1 mgIn Stock
$55.00
1
5 mgIn Stock
$205.00
1
10 mgIn Stock
$327.00
1
25 mgIn Stock
$750.00
1
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Citations

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    632, 686–694 (2024)
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    618, 1017–1023 (2023)
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    610, 366–372 (2022)
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    Cell
    187(9):2288-2304 (2024)
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    Cell
    183(7):1867-1883 (2020)
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    388(6745) (2025)
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    35, 97–116 (2025)
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    31, 1291–1307 (2021)

Description

N-Palmitoyl phenylalanine is an N-acyl amide that contains the long-chain saturated fatty acid palmitic acid conjugated via an amide bond to the essential amino acid L-phenylalanine. It inhibits pre-mRNA splicing in HeLa cell nuclear lysates (IC50 = ~150 ?M) but has no splicing activity in intact HeLa cells.1

References:
[1]. Effenberger, K.A., James, R.C., Urabe, V.K., et al.The natural product N-palmitoyl-L-leucine selectively inhibits late assembly of human spliceosomesJ. Biol. Chem.290(46)27524-27531(2015).

Product Documents

Purity:>95.00%Appearance:A solid
COASDSData Sheet

Chemical Properties

CAS No.
37571-96-3
Synonyms
N-Hexadecanoyl Phenylalanine
Chemical Name
N-(1-oxohexadecyl)-L-phenylalanine
SMILES
CCCCCCCCCCCCCCCC(N[C@@H](CC1=CC=CC=C1)C(O)=O)=O
Molecular Formula
C25H41NO3
Molecular Weight
403.6
Solubility
Ethanol: Sparingly soluble: 1-10 mg/ml
Storage
-20°C
General tips
Select a suitable solvent according to the product solubility data. Once prepared, aliquot the stock solution to avoid repeated freeze-thaw cycles.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.

CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility

g/mol

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