GLPBio

NM102

Catalog No.: GC78838Purity:>99.50%
NM102 is an ATP competitive mutation frequency decline ( Mfd ) protein inhibitor ( IC50 = 29 μM, K i = 27 μM) with potent antimicrobial activity.

Products are for research use only. Not for human use. We do not sell to patients.


NM102
Cas No.: 2094576-12-0
5mgIn Stock
$237.00
1
10mgIn Stock
$379.00
1

Citations

No citations are currently available for this product. Below are selected publications citing GlpBio products.
  • Nature cover
    Nature
    641, 529–536 (2025)
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    Nature
    628, 630–638 (2024)
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    Nature
    632, 686–694 (2024)
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    Nature
    618, 1017–1023 (2023)
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    Nature
    610, 366–372 (2022)
  • Cell cover
    Cell
    187(9):2288-2304 (2024)
  • Cell cover
    Cell
    183(7):1867-1883 (2020)
  • Science cover
    Science
    388(6745) (2025)
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    387(6739) (2025)
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    Science
    387(6734) (2025)
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    Cell Research
    35, 97–116 (2025)
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    Cell Research
    34, 683–706 (2024)
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    33, 273–287 (2023)
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    33, 546–561 (2023)
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    33, 904–922 (2023)
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    Cell Research
    31, 1291–1307 (2021)

Description

NM102 is an ATP competitive mutation frequency decline ( Mfd ) protein inhibitor ( IC50 = 29 μM, K i = 27 μM) with potent antimicrobial activity. NM102 protects against infections with antimicrobial resistant ESKAPE pathogens. NM102 exhibits activity in insects and mice. NM102 can be used for research of infections caused by Gram-negative bacteria [1].

References:
[1]. Tran SL, et al. An anti-virulence drug targeting the evolvability protein Mfd protects against infections with antimicrobial resistant ESKAPE pathogens. Nat Commun. 2025 Apr 28;16(1):3324.

Product Documents

Purity:>99.50%Appearance:A solid

Chemical Properties

CAS No.
2094576-12-0
Molecular Formula
C20H24N4O5S2
Molecular Weight
464.56
Solubility
DMSO: 5 mg/mL (10.76 mM; Need ultrasonic)
Storage
Store at -20°C
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.

CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility

g/mol

Reviews

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