NPR-C activator 1 (Compound 1) is an effective activator of the natriuretic peptide receptor C (NPR-C). C-type natriuretic peptide (CNP) participates in the regulation of vascular homeostasis. NPR-C activator 1 has been identified as an effective agonist (EC50-1 μ M) with good in vivo pharmacokinetic properties.
Citations
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Product Documents
Purity:>99.00%Appearance:A solid
Chemical Properties
CAS No.
2768328-61-4
SMILES
CC(NC1=CC=C(C=C1)NC2=NC=NC(NCCC(OC(C)(C)C)=O)=N2)=O
Molecular Formula
C18H24N6O3
Molecular Weight
372.42
Solubility
DMSO : 100 mg/mL (268.51 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Storage
-20°C
General tips
Select a suitable solvent according to the product solubility data. Once prepared, aliquot the stock solution to avoid repeated freeze-thaw cycles.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.
CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility
g/mol
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