NRG-1 protein, belonging to the structurally related peptide growth factor family of Human, originates from alternative splicing genes and induces Fn14 expression in MCF7 cells.
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Product Documents
Purity:≥ 95% as determined by reducing SDS-PAGEAppearance:Lyophilized powder
Chemical Properties
Purity
≥ 95% as determined by reducing SDS-PAGE
Source
E. coli
Physical Appearance
Lyophilized powder
Shipping Condition
Room temperature in continental US; may vary elsewhere.
Synonyms
rHuHeregulin-1 β1; ARIA; HRG; NRG1; Neuregulin-1
Amino Acid Sequence
SHLVKCAEKEKTFCVNGGECFMVKDLSNPSRYLCKCPNEFTGDRCQNYVMASFYKHLGIEFMEAE
Solubility
It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH2O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).
Apparent Molecular Weight
Approximately 8 kDa Da
Biological Activity
Measured in a serum-free cell proliferation assay using MCF-7 human breast cancer cells. The ED50 this effect is ≤ 2.158 ng/mL, corresponding to a specific activity is ≥ 4.6339×105 units/mg.
Formulation
It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH2O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).
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