NTRC-739 is a selective nonpeptide partial neurotensin receptor type 2 (NTS2) agonist with an EC 50 of 12 nM and a K i of 153 nM. NTRC-739 is 161-fold selective for NTS2 versus NTS1. NTRC-739 can be used for the study of chronic pain research [1].
References:
[1]. Thomas JB, et al. Identification of 1-({[1-(4-fluorophenyl)-5-(2-methoxyphenyl)-1H-pyrazol-3-yl]carbonyl}amino)cyclohexane carboxylic acid as a selective nonpeptide neurotensin receptor type 2 compound. J Med Chem. 2014 Jun 26;57(12):5318-32.
References:
[1]. Thomas JB, et al. Identification of 1-({[1-(4-fluorophenyl)-5-(2-methoxyphenyl)-1H-pyrazol-3-yl]carbonyl}amino)cyclohexane carboxylic acid as a selective nonpeptide neurotensin receptor type 2 compound. J Med Chem. 2014 Jun 26;57(12):5318-32.