GLPBio

pyCTZ

Catalog No.: GC70727Purity:>95.00%
COASDSData Sheet
pyCTZ (Pyridyl CTZ), a pyridyl Coelenterazine (CTZ) analog, and is an ATP-independent pyridyl substrate of LumiLuc luciferase.

Products are for research use only. Not for human use. We do not sell to patients.

pyCTZ
Cas No.: 2125486-34-0
1 mgIn Stock
$117.00
1
5 mgIn Stock
$270.00
1
10 mgIn Stock
$468.00
1
25 mgIn Stock
$882.00
1
Tel: (909) 407-4943 / (909) 689-7124Email: sales@glpbio.com

Citations

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    610, 366–372 (2022)
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    Cell
    187(9):2288-2304 (2024)
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    183(7):1867-1883 (2020)
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Description

pyCTZ (Pyridyl CTZ), a pyridyl Coelenterazine (CTZ) analog, and is an ATP-independent pyridyl substrate of LumiLuc luciferase. pyCTZ generates strong blue bioluminescence in the presence of luciferases. pyCTZ can be used for aequorin-based calcium sensing.

pyCTZ is comparable to native CTZ for bioluminescence intensity when pairs with aequorin[1].

References:
[1]. Yeh HW, et, al. ATP-Independent Bioluminescent Reporter Variants To Improve in Vivo Imaging. ACS Chem Biol. 2019 May 17;14(5):959-965.

Product Documents

Purity:>95.00%Appearance:A solid
COASDSData Sheet

Chemical Properties

CAS No.
2125486-34-0
Molecular Formula
C25H20N4O
Molecular Weight
392.45
Solubility
Methanol : 41.67 mg/mL (106.18 mM; Need ultrasonic)DMSO : 33.33 mg/mL (84.93 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Storage
-20°C, protect from light
General tips
Select a suitable solvent according to the product solubility data. Once prepared, aliquot the stock solution to avoid repeated freeze-thaw cycles.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.

CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility

g/mol

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