GLPBio

Pyrrothiogatain

Catalog No.: GC75235Purity:>96.00%
COASDSData Sheet
Pyrrothiogatain is an inhibitor for transcription factor GATA.

Products are for research use only. Not for human use. We do not sell to patients.

Pyrrothiogatain
Cas No.: 477888-48-5
5 mgIn Stock
$27.00
1
10 mgIn Stock
$43.00
1
25 mgIn Stock
$81.00
1
50 mgIn Stock
$130.00
1
100 mgIn Stock
$194.00
1
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Citations

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    Nature
    641, 529–536 (2025)
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    628, 630–638 (2024)
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    632, 686–694 (2024)
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    618, 1017–1023 (2023)
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    Nature
    610, 366–372 (2022)
  • Cell cover
    Cell
    187(9):2288-2304 (2024)
  • Cell cover
    Cell
    183(7):1867-1883 (2020)
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    Science
    388(6745) (2025)
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    387(6739) (2025)
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    387(6734) (2025)
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    Cell Research
    35, 97–116 (2025)
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    34, 683–706 (2024)
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    33, 273–287 (2023)
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    33, 546–561 (2023)
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    33, 904–922 (2023)
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    Cell Research
    31, 1291–1307 (2021)

Description

Pyrrothiogatain is an inhibitor for transcription factor GATA. Pyrrothiogatain inhibits the DNA-binding activity of GATA3, inhibits the T helper 2 (Th2) cell differentiation and expression of Th2 cytokines. Pyrrothiogatain is potential in Th2 related allergic disorders[1].

References:
[1]. Nomura S, et al., Pyrrothiogatain acts as an inhibitor of GATA family proteins and inhibits Th2 cell differentiation in vitro. Sci Rep. 2019 Nov 22;9(1):17335.

Product Documents

Purity:>96.00%Appearance:A solid
COASDSData Sheet

Chemical Properties

CAS No.
477888-48-5
Molecular Formula
C11H11NO2S
Molecular Weight
221.28
Solubility
DMSO: 125 mg/mL (564.90 mM; Need ultrasonic)
Storage
-20°C
General tips
Select a suitable solvent according to the product solubility data. Once prepared, aliquot the stock solution to avoid repeated freeze-thaw cycles.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.

CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility

g/mol

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