R06039-691 is a neuropeptide S receptor ( NPSR ) agonist with an EC 50 of 93 nM. By activating NPSR, R06039-691 participates in the regulation of multiple biological functions including arousal, stress and anxiety responses, memory processes, and food intake. R06039-691 can be used for research on NPSR -related diseases such as anxiety, insomnia, narcolepsy, and cognitive impairment [1].
In Vitro, R06039-691 acts as an agonist of NPSR in RD-HGA16 cells stably expressing human NPS receptor, with an EC50 of 93 nM[1].
References:
[1]. Runyon S, et al. Neuropeptide S receptor (NPSR) agonists. International Patent Application No. WO 2017/176461 A1. Published October 12, 2017.
In Vitro, R06039-691 acts as an agonist of NPSR in RD-HGA16 cells stably expressing human NPS receptor, with an EC50 of 93 nM[1].
References:
[1]. Runyon S, et al. Neuropeptide S receptor (NPSR) agonists. International Patent Application No. WO 2017/176461 A1. Published October 12, 2017.