Cyclic GMP-AMP Synthase
Products Related to Cyclic GMP-AMP Synthase(6)
- GC33093Decoyinine (Angustmycin A)CAS: 2004-04-8Purity: >98%
Decoyinine is a selective inhibitor of GMP synthetase (GMPS).
- GC37570RU.521CAS: 2262452-06-0Purity: >98.00%
RU.521 (RU320521) is a potent and selective cyclic GMP-AMP synthase (cGAS) inhibitor that binds to the catalytic domain of cGAS, thereby inhibiting the activation of cGAS by dsDNA. The IC 50 value of RU.521 in inhibiting cGAS-mediated signal transduction is 700nM.
- GC79068Telomeric G4s ligand 2CAS: 3094716-52-3Purity: >98%
Telomeric G4s ligand 2 is an orally active, selective ligand of telomeric G-quadruplex (G4), with an IC 50 of 0.4 μM.
- GC79366IptocigistatCAS: 3047739-67-0Purity: >98%
Iptocigistat (Iptocigistatum) is a cyclic GMP-AMP synthase ( cGAS ) inhibitor.
| Catalog No. | Product Name | CAS No. | Purity | Structure |
|---|---|---|---|---|
| GC33093 | Decoyinine (Angustmycin A) | 2004-04-8 | >98% | |
Decoyinine is a selective inhibitor of GMP synthetase (GMPS). | ||||
| GC37570 | RU.521 | 2262452-06-0 | >98.00% | |
RU.521 (RU320521) is a potent and selective cyclic GMP-AMP synthase (cGAS) inhibitor that binds to the catalytic domain of cGAS, thereby inhibiting the activation of cGAS by dsDNA. The IC 50 value of RU.521 in inhibiting cGAS-mediated signal transduction is 700nM. | ||||
| GC62664 | G140 | 2369751-07-3 | >98.00% | |
G140 is a potent and selective inhibitor of cyclic GMP-AMP synthase (cGAS), with IC50s of 14.0?nM and 442?nM for h-cGAS and m-cGAS, respectively. | ||||
| GC71470 | cGAS-IN-2 | 2765273-11-6 | - | |
cGAS-IN-2 (compound 109) is a potent inhibitor of Cyclic GMP-AMP Synthase (cGAS), with IC50 of 0.01512 μM for h-cGAS. | ||||
| GC79068 | Telomeric G4s ligand 2 | 3094716-52-3 | >98% | |
Telomeric G4s ligand 2 is an orally active, selective ligand of telomeric G-quadruplex (G4), with an IC 50 of 0.4 μM. | ||||
| GC79366 | Iptocigistat | 3047739-67-0 | >98% | |
Iptocigistat (Iptocigistatum) is a cyclic GMP-AMP synthase ( cGAS ) inhibitor. | ||||