Ro 25-1553 TFA is a 31 amino acid vasoactive intestinal peptide (VIP) analog, that acts as an agonist for VIP2 receptor ( VPAC2 receptor ). Ro 25-1553 TFA exhibits a bronchodilator effect in nerve-induced or Carbachol -induced tracheal smooth muscle contraction in guinea pig model [1].
References:
[1]. Källström BL, et al., Bronchodilating properties of the VIP receptor agonist Ro 25-1553 compared to those of formoterol on the guinea-pig isolated trachea. Eur J Pharmacol. 2001 Nov 2;430(2-3):335-40.
References:
[1]. Källström BL, et al., Bronchodilating properties of the VIP receptor agonist Ro 25-1553 compared to those of formoterol on the guinea-pig isolated trachea. Eur J Pharmacol. 2001 Nov 2;430(2-3):335-40.
















