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SCH 28080

Catalog No.GC11151

H+,K+-ATPase inhibitor

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SCH 28080 Chemical Structure

Cas No.: 76081-98-6

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

SCH28080 inhibits gastric H+/K+-ATPase by K+-competitive binding, with an IC50 value of 20 nM in rabbit microsomal membranes[1]. Antisecretory and cytoprotective activities[2].

[1]. Scott CK, et al. Studies on the mechanism of action of the gastric microsomal (H+ + K+)-ATPase inhibitors SCH 32651 and SCH 28080. Biochem Pharmacol. 1987 Jan 1;36(1):97-104.
[2]. Long JF, et al. Gastric antisecretory and cytoprotective activities of SCH 28080. J Pharmacol Exp Ther. 1983 Jul;226(1):114-20.


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