GLPBio

Shepherdine

Catalog No.: GC81760Purity:>98.00%
Shepherdine, a harmala-type indole and tetrahydro-β-carboline alkaloid, is an antioxidant.

Products are for research use only. Not for human use. We do not sell to patients.


Shepherdine
Cas No.: 3000-36-0
1mgIn Stock
$176.00
1
5mgIn Stock
$491.00
1

Citations

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    Nature
    641, 529–536 (2025)
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    628, 630–638 (2024)
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    632, 686–694 (2024)
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    618, 1017–1023 (2023)
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    Nature
    610, 366–372 (2022)
  • Cell cover
    Cell
    187(9):2288-2304 (2024)
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    Cell
    183(7):1867-1883 (2020)
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    Science
    388(6745) (2025)
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    387(6739) (2025)
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    Science
    387(6734) (2025)
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    Cell Research
    35, 97–116 (2025)
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    34, 683–706 (2024)
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    33, 273–287 (2023)
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    33, 546–561 (2023)
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    33, 904–922 (2023)
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    31, 1291–1307 (2021)

Description

Shepherdine, a harmala-type indole and tetrahydro-β-carboline alkaloid, is an antioxidant. Shepherdine scavenges free radicals via single electron transfer from its indole ring, forming an indolyl cation or neutral radical, and may convert to aromatic β-carbolines during this process. Shepherdine can be used for research on antioxidant activity [1].

In Vitro, Shepherdine (Compound 1) acts as a potent ABTS•+ radical scavenger in a cell-free assay[1].

References:
[1]. Herraiz T, et al. Tetrahydro-beta-carboline alkaloids occur in fruits and fruit juices. Activity as antioxidants and radical scavengers. J Agric Food Chem. 2003;51(24):7156-7161.

Product Documents

Purity:>98.00%Appearance:A solid

Chemical Properties

CAS No.
3000-36-0
Molecular Formula
C12H14N2O
Molecular Weight
202.25
Solubility
DMSO: 107 mg/mL (529.05 mM; Need ultrasonic)
Storage
Store at 4°C, sealed storage, away from moisture
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.

CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility

g/mol

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