SKF96067 |
| Catalog No.GC30418 |
SKF96067 is a reversible inhibitor of the gastric H+/K+-ATPase.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 115607-61-9
Sample solution is provided at 25 µL, 10mM.
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SKF96067 is a reversible inhibitor of the gastric H+/K+-ATPase.
SKF96067 inhibits K+-stimulated ATPase activity competitively with respect to the activating action K+, with a Ki value of 0.39 ± 0.05 μM. SKF96067 also inhibits hydrogen ion transport. SKF96067 inhibits ATPase activity with an IC50 value of 60 ± 10 μM at pH 7.0, in the presence of 100 mM NaCl and 1 mM KCl[1].
[1]. Keeling DJ, et al. SK&F 96067 is a reversible, lumenally acting inhibitor of the gastric (H+ + K+)-ATPase. Biochem Pharmacol. 1991 Jun 21;42(1):123-30.
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