AHR-1911 (10-Undecen-1-yl-Thiopseudourea Iodide;Isothiuronium) is a thiourea-based anti-inflammatory and anti-tumor agent that has an improving effect on burned skin. AHR-1911 produces histamine-like effects when injected intradermally and may reduce arterial pressure in anesthetized dogs. AHR-1911 inhibits tumor growth and reduces microsomal and C-polysome protein synthesis.
References:
[1]. Fuenmayor L, et al. Effect of 10 undecen 1-YL thiopseudourea iodide (AHR-1911) on rat arterial pressure and capillary permeability. Proc Soc Exp Biol Med. 1973 Jun;143(2):568-71.
[2]. González-Cadavid NF, et al. Inhibition of translation in liver polyribosomes by a new substituted thiopseudourea with antitumour action. Biochem J. 1974 Feb;138(2):129-41.