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Carboxypeptidase

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A carboxypeptidase (CP) is an enzyme involved in the catabolism of proteins that cleaves amino acids from the C-terminal of proteins or large peptides through rapid hydrolysis at the last stages of protein cleavage. So far thirteen mammalian CPs encoded by thirteen known members of the metallocarboxypeptidase gene family and one human-specific CP (CPA3) have been identified. Based primarily on amino acid sequence similarities, metallocarboxypeptidases are divided into two subfamilies, including CPA/B family (CPA1, CPA2, CPB, MK-CPA and KPU) and CPN/E family (CPE/H, CPM, CPN, CPD, CPZ, CPX1, CPX2 and AEBP1). All members in CPA/B family are approximately 34-36 kDa proteins of optimal pH=7; while all members in CPN/E family range in size and pH optima. 

Products Related to Carboxypeptidase(10)

  • GC11804 structure
    GC118042-Guanidinoethylmercaptosuccinic Acid
    CAS: 77482-44-1
    Purity: >98%

    El Ácido 2-guanidinoetilmercaptosuccÍnico (Ácido 2-guanidinoetilmercaptosuccÍnico) es un potente inhibidor especÍfico de la enzima de procesamiento similar a la carboxipeptidasa B (encefalina convertasa) con un valor Ki de 8,8 nM.

  • GC13467 structure
    GC13467PMPA (NAALADase inhibitor)
    CAS: 173039-10-6
    Purity: >98.00%

    A potent inhibitor of GCP II/NAALADase

  • GC17937 structure
    GC179372-MPPA
    CAS: 254737-29-6
    Purity: >98.00%

    2-MPPA (GPI-5693) es un inhibidor de la glutamato carboxipeptidasa II (GCP II; PSMA) selectivo y activo por vÍa oral con una IC50 de 90 nM.

  • GC18065 structure
    GC18065ZJ 43
    CAS: 723331-20-2
    Purity: >98%
  • GC35608 structure
    GC35608Carboxypeptidase G2 (CPG2) Inhibitor
    CAS: 192203-60-4
    Purity: >98.00%

    El inhibidor de carboxipeptidasa G2 (CPG2) es un nuevo inhibidor de carboxipeptidasa G2 (CPG2), agentes antitumorales.

  • GC35741 structure
    GC35741CPA inhibitor
    CAS: 223532-02-3
    Purity: >99.50%

    El inhibidor de CPA (inhibidor de la carboxipeptidasa; compuesto 5) es un potente inhibidor de la carboxipeptidasa A (CPA) con una Ki de 0,32 μM.

  • GC60471 structure
    GC604712-Benzylsuccinic acid
    CAS: 884-33-3
    Purity: >98.00%

    El Ácido 2-bencilsuccÍnico (Ácido DL-bencilsuccÍnico) es un potente inhibidor de la carboxipeptidasa A (CPA).

  • GC63338 structure
    GC63338GCPII-IN-1 TFA
    CAS: 1269794-89-9
    Purity: >98%

    GCPII-IN-1 TFA es un andamio inhibidor de glutamato carboxipeptidasa II (GCPII o PSMA) con una Ki de 44,3 nM.

  • GC72702 structure
    GC72702Mergetpa
    CAS: 77102-28-4
    Purity: >95.00%

    Mergetpa es un inhibide carboxipeptidasa usado para bloquear la conversión de cininas y antagondel receptor B2 a metabolique carecen de arginc-terminal.

  • GC79578 structure
    GC79578PrCP-7414
    CAS: 1252037-41-4
    Purity: >99.50%

    PrCP-7414 is a prolyl carboxypeptidase ( PRCP ) inhibitor.