DANP dihydrochloride is a bulge base recognition probe that strongly and specifically binds to the single cytosine and thymine bulges. DANP dihydrochloride could stabilize not only a single cytosine but also the thymine bulge in duplex DNA [1].
References:
[1]. Suda H, et al. N,N'-Bis(3-aminopropyl)-2,7-diamino-1,8-naphthyridine stabilized a single pyrimidine bulge in duplex DNA. Bioorg Med Chem. 2005 Jul 15;13(14):4507-12.
References:
[1]. Suda H, et al. N,N'-Bis(3-aminopropyl)-2,7-diamino-1,8-naphthyridine stabilized a single pyrimidine bulge in duplex DNA. Bioorg Med Chem. 2005 Jul 15;13(14):4507-12.