GLPBio

Drug Metabolite

Drug metabolite results when a drug is metabolized into a modified form which continues to produce effects. Drug metabolism redox reactions such as heteroatom dealkylations, hydroxylations, heteroatom oxygenations, reductions, and dehydrogenations can yield active metabolites, and in rare cases even conjugation reactions can yield an active metabolite.

Products Related to Drug Metabolite(546)

  • GC10822 structure
    GC10822Clozapine N-oxide (CNO)
    CAS: 34233-69-7
    Purity: >98.00%

    Clozapine N-oxide (CNO) es un potente antagonista de la dopamina y también un potente y selectivo agonista del receptor muscarínico M4 (EC 50 =11 nM) [5，6] .

  • GC11155 structure
    GC11155Omeprazole sulfone
    CAS: 88546-55-8
    Purity: >98%

    El omeprazol sulfona es un metabolito del omeprazol, que es un inhibidor de la bomba de protones.

  • GC11989 structure
    GC11989Nortriptyline (hydrochloride)
    CAS: 894-71-3
    Purity: >99.50%

    La nortriptilina (clorhidrato) (clorhidrato de desmetilamitriptilina), el principal metabolito activo de la amitriptilina, es un antidepresivo tricíclico que se usa para aliviar los síntomas de la depresión.

  • GC12685 structure
    GC12685Ercalcitriol
    CAS: 60133-18-8
    Purity: >99.00%

    A potent agonist of the vitamin D receptor

  • GC14762 structure
    GC14762Palifosfamide
    CAS: 31645-39-3
    Purity: >98%

    An active metabolite of ifosfamide

  • GC14780 structure
    GC14780Oseltamivir acid
    CAS: 187227-45-8
    Purity: >98.00%

    A neuraminidase inhibitor and antiviral

  • GC15168 structure
    GC15168Urolithin A
    CAS: 1143-70-0
    Purity: >98.50%

    Urolithin A es un metabolito generado a partir del ácido elágico y las elagitaninas, que actúa como un potente inhibidor de la tirosinasa (valor de IC 50 de 71.44±10.07μmol/L) y la monoaminooxidasa A (valor de IC 50 de 29.41±9.01μmol/L).

  • GC16292 structure
    GC16292Equol
    CAS: 94105-90-5
    Purity: >98.00%

    Equol es el racemato de equol.

  • GC16333 structure
    GC16333Cycloguanil (hydrochloride)
    CAS: 152-53-4
    Purity: >99.50%

    El cicloguanil (clorhidrato), el metabolito activo del proguanil, actúa sobre los esquizontes del paludismo en eritrocitos y hepatocitos.

  • GC16553 structure
    GC16553N-Desmethylclozapine
    CAS: 6104-71-8
    Purity: >99.50%

    La N-Desmetilclozapina es un metabolito activo principal del fÁrmaco antipsicÓtico atÍpico Clozapina.

  • GC18194 structure
    GC181944-Epidoxycycline
    CAS: 6543-77-7
    Purity: >98%

    4-Epidoxycycline is the 4-epimer hepatic metabolite of the antibiotic doxycycline .

  • GC18219 structure
    GC182196-hydroxy Warfarin
    CAS: 17834-02-5
    Purity: >98.00%

    6-hydroxy Warfarin is a metabolite of (+)-warfarin , which is a weaker vitamin K antagonist than (-)-warfarin .

  • GC18335 structure
    GC183356β-hydroxy Dexamethasone
    CAS: 55879-47-5
    Purity: >98%

    6β-hydroxy Dexamethasone is a metabolite of dexamethasone that is more hydrophilic than the parent compound.

  • GC18417 structure
    GC184174-hydroxy Xylazine
    CAS: 145356-32-7
    Purity: >97.50%

    4-hidroxi Xilazina es un metabolito de la xilazina.

  • GC18425 structure
    GC184254-hydroxy Atorvastatin lactone
    CAS: 163217-70-7
    Purity: >98%

    4-hydroxy Atorvastatin lactone is a metabolite of atorvastatin , an HMG-CoA reductase inhibitor present in formulations that have been used to treat hypercholesterolemia and certain dyslipidemias.

  • GC18439 structure
    GC18439Doxorubicinone
    CAS: 24385-10-2
    Purity: >95.00%

    La doxorrubicinana es un metabolito de un agente de quimioterapia contra el cÁncer, la doxorrubicina. La doxorrubicina es un potente inhibidor de la topoisomerasa I y la topoisomerasa II del ADN humano con IC50 de 0,8 μM y 2,67 μM, respectivamente.

  • GC18455 structure
    GC18455Digoxigenin Monodigitoxoside
    CAS: 5352-63-6
    Purity: >98%

    El monodigitoxÓsido de digoxigenina es un inhibidor de la Na+/K+ ATPasa y un metabolito glucÓsido cardÍaco de la digoxina.

  • GC18466 structure
    GC184665,6-epoxy-13-cis Retinoic Acid
    CAS: 81444-57-7
    Purity: >98%

    5,6-epoxy-13-cis Retinoic acid is a metabolite of 13-cis retinoic acid.

  • GC18527 structure
    GC185274'-hydroxy Flurbiprofen
    CAS: 52807-12-2
    Purity: >98%

    A major active metabolite of flurbiprofen

  • GC18539 structure
    GC185394-Hydroxyretinoic acid (4-HRA)
    CAS: 66592-72-1
    Purity: >98.00%

    4-Hydroxyretinoic acid (4-HRA) is a naturally occurring, primary metabolite derived from all-trans retinoic acid (ATRA) via cytochrome P450 enzyme metabolism.

  • GC18542 structure
    GC185425,6-dihydro-5-Fluorouracil
    CAS: 696-06-0
    Purity: >95.00%

    5,6-dihydro-5-Fluorouracil (5-FUH2) is formed by the hydrogenation of 5-fluorouracil via the enzyme dihydropyrimidine dehydrogenase (DPD).

  • GC18569 structure
    GC18569Propofol β-D-Glucuronide
    CAS: 114991-26-3
    Purity: >98.00%

    Propofol β-D-Glucuronide es un metabolito del propofol y se utiliza ampliamente como marcador para identificar el estado metabólico del propofol en animales.

  • GC18582 structure
    GC185825'-hydroxy Meloxicam
    CAS: 130262-92-9
    Purity: >98%

    A metabolite of meloxicam

  • GC18596 structure
    GC18596(±)-2-propyl-4-Pentenoic Acid
    CAS: 1575-72-0
    Purity: >98.00%

    El Ácido (±)-2-propil-4-pentenoico (4-en-VPA) es un metabolito tÓxico principal del Ácido valproico.