Filastatin |
| Catalog No.GC60841 |
La filastatina es un inhibidor de larga duraciÓn de la filamentaciÓn de Candida albicans.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 431996-53-1
Sample solution is provided at 25 µL, 10mM.
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Filastatin is a long-lasting inhibitor of Candida albicans filamentation. Filastatin inhibits adhesion by multiple pathogenic Candida species with an IC50 of ~3 μM in the GFP-based adhesion assay. Filastatin inhibits fungal adhesion to polystyrene and human cells, the yeast-to-hyphal morphological transition, induction of the hyphal-specific HWP1 promoter. Filastatin has potent antifungal effect[1].
[1]. Ahmed Fazly, et al. Chemical screening identifies filastatin, a small molecule inhibitor of Candida albicans adhesion, morphogenesis, and pathogenesis. Proc Natl Acad Sci U S A. 2013 Aug 13;110(33):13594-9.
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