CP-060 |
| Catalog No.GC35738 |
CP-060 es un potente antagonista de Ca2+, inhibe la sobrecarga de Ca2+ y posee actividades antioxidantes y cardioprotectoras.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 180090-15-7
Sample solution is provided at 25 µL, 10mM.
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CP-?060 is a potent Ca2+ antagonist, inhibits Ca2+ overload and possesses antioxidant and cardioprotective activities.
CP-?060 (0.5, 5 μM) inhibits rabbit LDL oxidation induced by soybean lipoxygenase by 12.9% and 3.0%, respectively[1].
CP-?060 (100 mg/kg, i.v.) increases the coronary blood flow by 96% in anesthetized dogs[2].
[1]. Kato T, et al. Novel calcium antagonists with both calcium overload inhibition and antioxidant activity. 1. 2-(3, 5-di-tert-butyl-4-hydroxyphenyl)-3-(aminopropyl)thiazolidinones. J Med Chem. 1998 Oct 22;41(22):4309-16. [2]. Kato T, et al. Novel calcium antagonists with both calcium overload inhibition and antioxidant activity. 2. Structure-activity relationships of thiazolidinone derivatives. J Med Chem. 1999 Aug 12;42(16):3134-46.
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