GDC-0077 (RG6114) (Synonyms: GDC-0077; RG6114) |
| Catalog No.GC32710 |
GDC-0077 (RG6114) es un PI3Kα potente, disponible por vÍa oral y selectivo; inhibidor (CI50 = 0,038 nM). GDC-0077 (RG6114) ejerce su actividad uniéndose al sitio de uniÓn de ATP de PI3K, inhibiendo asÍ la fosforilaciÓn de PIP2 a PIP3. GDC-0077 (RG6114) es mÁs selectivo para PI3Kα mutante frente a tipo salvaje;.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2060571-02-8
Sample solution is provided at 25 µL, 10mM.
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GDC-0077 is an orally available PI3K inhibitor with potential antineoplastic activity. GDC-0077 is extracted from patent WO 2017001645 A1, formula I.
[1]. WO 2017001645 A1
Average Rating: 5 (Based on Reviews and 39 reference(s) in Google Scholar.)
GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.
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