2',3'-Dideoxyadenosine-5'-O-(1-Thiotriphosphate) is a sugar modified nucleoside triphosphate where the 2' and 3' hydroxyl groups are absent, resulting in chain termination. This ddATP analog also contains a 1-Thiotriphosphate which results in a nuclease resistant phosphorothioate linkage. The inability of polymerases to extend from a dideoxy nucleotide causes chain termination and is useful in antiviral research and in a variety of biotechnology applications.
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Purity:>90.00%Appearance:A solid
Propiedades químicas (Chemical Properties)
Pureza
>90.00%
Coeficiente de extinción
15,400 Lmol-1cm-1 at 258 nm
Fórmula
C10H16N5O10P3S (free acid)
M.Wt
491.20 g/mole (free acid)
Forma salina
Li+
Concentración
100 mM
Tampón
H2O
Almacenamiento
-20°C or below
Sinónimos
Alpha Thiol ddATP, 1-Thio-ddATP
Esqueleto
5'-O-(1-Thiotriphosphate)
Análogo de base
Adenosine
Tipo de azúcar
2'-3'-Dideoxy
Categoría de nucleótido
Phosphate Modified
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