GLPBio

2',3'-Dideoxyadenosine-5'-O-(1-Thiotriphosphate)

Catalog No.: GN20162Purity:>90.00%

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2',3'-Dideoxyadenosine-5'-O-(1-Thiotriphosphate)
1µmoleIn Stock
$183.00
1
5µmoleIn Stock
$855.00
1
10µmoleIn Stock
$1,507.00
1

Citas (Citations)

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  • Nature cover
    Nature
    641, 529–536 (2025)
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    Nature
    628, 630–638 (2024)
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    Nature
    632, 686–694 (2024)
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    Nature
    618, 1017–1023 (2023)
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    Nature
    610, 366–372 (2022)
  • Cell cover
    Cell
    187(9):2288-2304 (2024)
  • Cell cover
    Cell
    183(7):1867-1883 (2020)
  • Science cover
    Science
    388(6745) (2025)
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    Science
    387(6739) (2025)
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    Science
    387(6734) (2025)
  • Cell Research cover
    Cell Research
    35, 97–116 (2025)
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    Cell Research
    34, 683–706 (2024)
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    Cell Research
    33, 273–287 (2023)
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    Cell Research
    33, 546–561 (2023)
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    Cell Research
    33, 904–922 (2023)
  • Cell Research cover
    Cell Research
    31, 1291–1307 (2021)

Descripción (Description)

2',3'-Dideoxyadenosine-5'-O-(1-Thiotriphosphate) is a sugar modified nucleoside triphosphate where the 2' and 3' hydroxyl groups are absent, resulting in chain termination. This ddATP analog also contains a 1-Thiotriphosphate which results in a nuclease resistant phosphorothioate linkage. The inability of polymerases to extend from a dideoxy nucleotide causes chain termination and is useful in antiviral research and in a variety of biotechnology applications.

Documentos del producto (Product Documents)

Purity:>90.00%Appearance:A solid

Propiedades químicas (Chemical Properties)

Pureza
>90.00%
Coeficiente de extinción
15,400 Lmol-1cm-1 at 258 nm
Fórmula
C10H16N5O10P3S (free acid)
M.Wt
491.20 g/mole (free acid)
Forma salina
Li+
Concentración
100 mM
Tampón
H2O
Almacenamiento
-20°C or below
Sinónimos
Alpha Thiol ddATP, 1-Thio-ddATP
Esqueleto
5'-O-(1-Thiotriphosphate)
Análogo de base
Adenosine
Tipo de azúcar
2'-3'-Dideoxy
Categoría de nucleótido
Phosphate Modified

Reviews

Review for 2',3'-Dideoxyadenosine-5'-O-(1-Thiotriphosphate)

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