GLPBio

JT71

Catalog No.: GC78829Purity:>99.00%
COASDSData Sheet
JT71 is an inhibitor of the transcriptional activator MrkH of type III fimbriae in Klebsiella pneumoniae.

Los productos son exclusivamente para uso en investigación. No aptos para uso humano. No vendemos a pacientes.

JT71
Cas No.: 380887-90-1
5mgIn Stock
$72.00
1
10mgIn Stock
$115.00
1
25mgIn Stock
$207.00
1
50mgIn Stock
$331.00
1
100mgIn Stock
$530.00
1
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Citas (Citations)

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    Nature
    641, 529–536 (2025)
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    628, 630–638 (2024)
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    632, 686–694 (2024)
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    618, 1017–1023 (2023)
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    Nature
    610, 366–372 (2022)
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    Cell
    187(9):2288-2304 (2024)
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    Cell
    183(7):1867-1883 (2020)
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    Science
    388(6745) (2025)
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    387(6739) (2025)
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    387(6734) (2025)
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    35, 97–116 (2025)
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    34, 683–706 (2024)
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    33, 273–287 (2023)
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    33, 546–561 (2023)
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    33, 904–922 (2023)
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    31, 1291–1307 (2021)

Descripción (Description)

JT71 is an inhibitor of the transcriptional activator MrkH of type III fimbriae in Klebsiella pneumoniae. JT71 reduces the activity of the mrkA promoter in Klebsiella pneumoniae, effectively inhibiting the formation of biofilms by Klebsiella pneumoniae, while not affecting the cell's viability. JT71 can be used for research on Klebsiella pneumoniae infections [1].

References:
[1]. Wilksch JJ, et al. Chemical inhibition of MrkH-dependent activation of type 3 fimbriae synthesis and biofilm formation by Klebsiella pneumoniae. NPJ Biofilms Microbiomes. 2025 Nov 20;11(1):212.

Documentos del producto (Product Documents)

Purity:>99.00%Appearance:A solid
COASDSData Sheet

Propiedades químicas (Chemical Properties)

N.º CAS
380887-90-1
Fórmula molecular
C18H18N2O2S
Peso molecular
326.41
Solubilidad
DMSO: 4.17 mg/mL (12.78 mM; Need ultrasonic)
Almacenamiento
Store at -20°C
Condiciones de envío
Las muestras de evaluación se envían con acumuladores de frío. Los demás tamaños se envían a temperatura ambiente o, previa solicitud, con acumuladores de frío.

Calculadoras (Calculators)Molaridad / Dilución / Peso molecular / Conversión de unidades / Formulación in vivo / Solubilidad

g/mol

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