JWH 309 is a synthetic cannabinoid (CB) that displays high affinities for both the central CB1 receptor (Ki = 41 nM) and the peripheral CB2 receptor (Ki = 49 nM). [1] The physiological and toxicological properties of this compound have not been examined. This product is intended for forensic and research applications.
Reference:
[1]. Huffman, J.W., Padgett, L.W., Isherwood, M.L., et al. 1-Alkyl-2-aryl-4-(1-naphthoyl)pyrroles: New high affinity ligands for the cannabinoid CB1 and CB2 receptors. Bioorg. Med. Chem. Lett. 16(20), 5432-5435 (2006).