GLPBio

NRG1-beta 1 Protein, Human

Catalog No.: GC26535Purity:≥ 95% as determined by reducing SDS-PAGE
COASDSData Sheet

NRG-1 protein, belonging to the structurally related peptide growth factor family of Human, originates from alternative splicing genes and induces Fn14 expression in MCF7 cells.

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NRG1-beta 1 Protein, Human
2μgIn Stock
$39.00
1
10μgIn Stock
$108.00
1
50μgIn Stock
$225.00
1
100μgIn Stock
$360.00
1
Tel: (909) 407-4943 / (909) 689-7124Email: sales@glpbio.com

Citas (Citations)

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    Nature
    641, 529–536 (2025)
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    Nature
    628, 630–638 (2024)
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    Nature
    632, 686–694 (2024)
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    Nature
    618, 1017–1023 (2023)
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    Nature
    610, 366–372 (2022)
  • Cell cover
    Cell
    187(9):2288-2304 (2024)
  • Cell cover
    Cell
    183(7):1867-1883 (2020)
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    Science
    388(6745) (2025)
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    387(6739) (2025)
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    Science
    387(6734) (2025)
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    Cell Research
    35, 97–116 (2025)
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    Cell Research
    34, 683–706 (2024)
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    33, 273–287 (2023)
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    Cell Research
    33, 546–561 (2023)
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    33, 904–922 (2023)
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    Cell Research
    31, 1291–1307 (2021)

Descripción (Description)

NRG-1 protein, belonging to the structurally related peptide growth factor family of Human, originates from alternative splicing genes and induces Fn14 expression in MCF7 cells.

Documentos del producto (Product Documents)

Purity:≥ 95% as determined by reducing SDS-PAGEAppearance:Lyophilized powder
COASDSData Sheet

Propiedades químicas (Chemical Properties)

Pureza
≥ 95% as determined by reducing SDS-PAGE
Fuente
E. coli
Aspecto físico
Lyophilized powder
Condiciones de envío
Room temperature in continental US; may vary elsewhere.
Sinónimos
rHuHeregulin-1 β1; ARIA; HRG; NRG1; Neuregulin-1
Secuencia de aminoácidos
SHLVKCAEKEKTFCVNGGECFMVKDLSNPSRYLCKCPNEFTGDRCQNYVMASFYKHLGIEFMEAE
Solubilidad
It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH2O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).
Peso molecular aparente
Approximately 8 kDa Da
Actividad biológica
Measured in a serum-free cell proliferation assay using MCF-7 human breast cancer cells. The ED50 this effect is ≤ 2.158 ng/mL, corresponding to a specific activity is ≥ 4.6339×105 units/mg.
Formulación
It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH2O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

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